HealthDay News recently reported “In the field of radiation oncology, we often assume that the highest dose that the body can tolerate will be most effective at killing cancer.” Dr. Den, the study’s senior author, explains. “Our results argue that this may not be the case, at least not with lower-risk prostate cancer patients.”
The researchers compiled 12 studies that assessed the use of external beam radiation treatment and pooled data from these clinical trials, which included more than 6,800 patients.
There was a drop in prostate-specific antigen (PSA) levels as patients received higher doses of radiation, and the researchers observed no uptick in adverse event, meaning that getting more radiation isn’t harmful. But, it did not lower rates of the prostate cancer spreading through the body or raise survival rates over the long-term, suggesting higher doses aren’t necessarily helpful either.
“This study suggests that our reliance on the PSA test as a proxy for patient outcomes may not as useful as many researchers thought,” said Dr. Den.
The study was also covered by CLTV, WQAD, and Renal & Urology News.